Switched my prompt from a desert to a flooded city and the story wrote itself

I was stuck on a sci-fi piece, so I changed the setting from a dry wasteland to a submerged Atlanta. The characters suddenly had immediate problems to solve, like finding air pockets and avoiding mutated wildlife. Has forcing a drastic setting change ever unlocked a story for you?

Last month I finally fixed a squeaky floorboard in my 1920s house... the trick was finding the right spot to put the screw.